Detailed summary for TMA19:
Protein that associates with ribosomes; homolog of translationally controlled tumor protein; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and relocates to the mitochondrial outer surface upon oxidative stress
After induction of apoptosis or mild oxidative stress, a protein reversibly translocates from the cytoplasm to mitochondria, where it is associated with the outer surface
- ROS production
- Rinnerthaler, M., et al. (2006) MMI1 (YKL056c, TMA19), the yeast orthologue of the translationally controlled tumor protein (TCTP) has apoptotic functions and interacts with both microtubules and mitochondria, Biochim Biophys Acta, 1757, 631-638.
- Carmona-Gutierrez, D., et al. (2010) Apoptosis in yeast: triggers, pathways, subroutines, Cell Death Differ, 17, 763-773.
Gene Expression Atlas: