Predicted motif cluster

An integrated network of protein-protein interactions (Szklarczyk et al.) and transcriptional regulations interactions (Abdulrehman et al. and Harbison et al.) among apoptosis genes was used to identify clustered motifs using CyClus3D, as described in Audenaert et al., CyClus3D: a Cytoscape plugin for clustering network motifs in integrated networks. Bioinformatics (2011). We identified a type of three-node network motifs which indicates transcriptional co-regulation of interacting proteins.

Notice: Edges are colored by their cluster membership.

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