Result summary


Detailed summary for NMA111:

NMA111


Systematic name:
YNL123W
Alias:
YNM3
Description:
Serine protease and general molecular chaperone; involved in response to heat stress and promotion of apoptosis; may contribute to lipid homeostasis; sequence similarity to the mammalian Omi/HtrA2 family of serine proteases

References


  • Fahrenkrog, B., Sauder, U. and Aebi, U. (2004) The S. cerevisiae HtrA-like protein Nma111p is a nuclear serine protease that mediates yeast apoptosis, J Cell Sci, 117, 115-126.
  • Walter, D., et al. (2006) The inhibitor-of-apoptosis protein Bir1p protects against apoptosis in S. cerevisiae and is a substrate for the yeast homologue of Omi/HtrA2, J Cell Sci, 119, 1843-1851.
  • Frohlich, K.U., Fussi, H. and Ruckenstuhl, C. (2007) Yeast apoptosis--from genes to pathways, Semin Cancer Biol, 17, 112-121.
  • Madeo, F., et al. (2009) Caspase-dependent and caspase-independent cell death pathways in yeast, Biochem Biophys Res Commun, 382, 227-231.
  • Belanger, K.D., et al. (2009) Nuclear localisation is crucial for the proapoptotic activity of the HtrA-like serine protease Nma111p, J Cell Sci, 122, 3931-3941.
  • Carmona-Gutierrez, D., et al. (2010) Apoptosis in yeast: triggers, pathways, subroutines, Cell Death Differ, 17, 763-773.

Cross references


SGD:
UniProt:
InterPro:
PDZ domain (IPR001478)
Peptidase S1C (IPR001940)
Trypsin-like cysteine/serine peptidase domain (IPR009003)
PSICQUIC View:
Gene Expression Atlas: