Result summary


Detailed summary for MCD1:

MCD1


Systematic name:
YDL003W
Alias:
PDS3, RHC21, SCC1
Description:
Essential alpha-kleisin subunit of the cohesin complex; required for sister chromatid cohesion in mitosis and meiosis; apoptosis induces cleavage and translocation of a C-terminal fragment to mitochondria; expression peaks in S phase
Related info:
RAD21 (Human cohesin)

References


  • Yang, H., Ren, Q. and Zhang, Z. (2008) Cleavage of Mcd1 by caspase-like protease Esp1 promotes apoptosis in budding yeast, Mol Biol Cell, 19, 2127-2134.
  • Madeo, F., et al. (2009) Caspase-dependent and caspase-independent cell death pathways in yeast, Biochem Biophys Res Commun, 382, 227-231.

Cross references


SGD:
UniProt:
InterPro:
Rad21/Rec8-like protein, C-terminal, eukaryotic (IPR006909)
Rad21/Rec8-like protein, N-terminal (IPR006910)
Rad21/Rec8-like protein, C-terminal (IPR023093)
PSICQUIC View:
Gene Expression Atlas: