Detailed summary for WWM1:
WW domain containing protein of unknown function; binds to Mca1p, a caspase-related protease that regulates H2O2-induced apoptosis; overexpression causes G1 phase growth arrest and clonal death that is suppressed by overexpression of MCA1
WW domain containing protein interacts with Metacaspase
- Madeo, F., et al. (2002) A caspase-related protease regulates apoptosis in yeast, Mol Cell, 9, 911-917.
- Szallies, A., Kubata, B.K. and Duszenko, M. (2002) A metacaspase of Trypanosoma brucei causes loss of respiration competence and clonal death in the yeast Saccharomyces cerevisiae, FEBS Lett, 517, 144-150.