Result summary


Detailed summary for RAS2:

RAS2


Systematic name:
YNL098C
Alias:
CTN5, CYR3, GLC5, TSL7
Description:
GTP-binding protein that regulates the nitrogen starvation response, sporulation, and filamentous growth; farnesylation and palmitoylation required for activity and localization to plasma membrane; homolog of mammalian Ras proto-oncogenes
Related info:
Hyper-activation of the Ras protein Ras2p, part of a signaling pathway upstream from PKA activation, increases apoptosis

References


  • Narasimhan, M.L., et al. (2005) Osmotin is a homolog of mammalian adiponectin and controls apoptosis in yeast through a homolog of mammalian adiponectin receptor, Mol Cell, 17, 171-180.
  • Leadsham, J.E., et al. (2009) Whi2p links nutritional sensing to actin-dependent Ras-cAMP-PKA regulation and apoptosis in yeast, J Cell Sci, 122, 706-715.

Cross references


SGD:
UniProt:
InterPro:
Small GTPase superfamily (IPR001806)
Small GTP-binding protein domain (IPR005225)
Small GTPase superfamily, Ras type (IPR020849)
P-loop containing nucleoside triphosphate hydrolase (IPR027417)
PSICQUIC View:
Gene Expression Atlas: