Result summary


Detailed summary for YSP1:

YSP1


Systematic name:
YHR155W
Description:
Mitochondrial protein; potential role in promoting mitochondrial fragmentation during programmed cell death in response to high levels of alpha-factor mating pheromone or the drug amiodarone; YSP1 has a paralog, SIP3, that arose from the whole genome duplication
Related info:
It is a yeast suicide protein

Pathway information


  • location
    • mitochondria
  • process
    • cytochrome c release
    • mitochondrial fragmentation
    • mitochondrial membrane permeabilization

References


  • Pozniakovsky, A.I., et al. (2005) Role of mitochondria in the pheromone- and amiodarone-induced programmed death of yeast, J Cell Biol, 168, 257-269.
  • Carmona-Gutierrez, D., et al. (2010) Apoptosis in yeast: triggers, pathways, subroutines, Cell Death Differ, 17, 763-773.

Cross references


SGD:
UniProt:
InterPro:
Pleckstrin homology domain (IPR001849)
Pleckstrin homology-like domain (IPR011993)
PSICQUIC View:
Gene Expression Atlas: