Result summary


Detailed summary for DRE2:

DRE2


Systematic name:
YKR071C
Description:
Component of the cytosolic Fe-S protein assembly (CIA) machinery; contains an Fe-S cluster that receives electrons from NADPH via the action of Tah18pin an early step in the CIA pathway; ortholog of human Ciapin1; protein abundance increases in response to DNA replication stress
Related info:
Dre2-Tah18 complex controls mitochondria integrity and cell death after oxidative stress in yeast

References


  • Vernis, L., et al. (2009) A newly identified essential complex, Dre2-Tah18, controls mitochondria integrity and cell death after oxidative stress in yeast, PLoS One, 4, e4376.
  • Netz, D.J., et al. (2010) Tah18 transfers electrons to Dre2 in cytosolic iron-sulfur protein biogenesis, Nat Chem Biol, 6, 758-765.

Cross references


SGD:
UniProt:
InterPro:
Anamorsin (IPR007785)
PSICQUIC View:
Gene Expression Atlas: