Result summary


Detailed summary for TAH18:

TAH18


Systematic name:
YPR048W
Description:
Conserved NAPDH-dependent diflavin reductase; component of an early step in the cytosolic Fe-S protein assembly (CIA) machinery; transfers electrons from NADPH to the Fe-S cluster of Dre2p; plays a pro-death role under oxidative stress; Tah18p-dependent nitric oxide synthesis confers high-temperature stress tolerance
Related info:
Dre2-Tah18 complex controls mitochondria integrity and cell death after oxidative stress in yeast

Pathway information


  • location
    • cytoplasm
    • mitochondria

References


  • Vernis, L., et al. (2009) A newly identified essential complex, Dre2-Tah18, controls mitochondria integrity and cell death after oxidative stress in yeast, PLoS One, 4, e4376.
  • Netz, D.J., et al. (2010) Tah18 transfers electrons to Dre2 in cytosolic iron-sulfur protein biogenesis, Nat Chem Biol, 6, 758-765.

Cross references


SGD:
UniProt:
InterPro:
Flavodoxin (IPR001094)
Oxidoreductase FAD/NAD(P)-binding (IPR001433)
Flavoprotein pyridine nucleotide cytochrome reductase (IPR001709)
FAD-binding, type 1 (IPR003097)
Flavodoxin/nitric oxide synthase (IPR008254)
Ferredoxin reductase-type FAD-binding domain (IPR017927)
Riboflavin synthase-like beta-barrel (IPR017938)
NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain-3 (IPR023173)
PSICQUIC View:
Gene Expression Atlas: