Detailed summary for STM1:
Protein required for optimal translation under nutrient stress; perturbs association of Yef3p with ribosomes; involved in TOR signaling; binds G4 quadruplex and purine motif triplex nucleic acid; helps maintain telomere structure; protein abundance increases in response to DNA replication stress; serves as a ribosome preservation factor both during quiescence and recovery
- protein degradation
- DNA fragmentation
- biological process
- molecular function
- cellular component
- Ligr, M., et al. (2001) The proteasomal substrate Stm1 participates in apoptosis-like cell death in yeast, Mol Biol Cell, 12, 2422-2432.
- Van Dyke, N., Baby, J. and Van Dyke, M.W. (2006) Stm1p, a ribosome-associated protein, is important for protein synthesis in Saccharomyces cerevisiae under nutritional stress conditions, J Mol Biol, 358, 1023-1031.
- Morton, C.O., Dos Santos, S.C. and Coote, P. (2007) An amphibian-derived, cationic, alpha-helical antimicrobial peptide kills yeast by caspase-independent but AIF-dependent programmed cell death, Mol Microbiol, 65, 494-507.