Result summary


Detailed summary for FYV10:

FYV10


Systematic name:
YIL097W
Alias:
GID9
Description:
Subunit of GID complex; involved in proteasome-dependent catabolite inactivation of gluconeogenic enzymes FBPase, PEPCK, and c-MDH; forms dimer with Rmd5p that is then recruited to GID Complex by Gid8p; contains a degenerate RING finger motif needed for GID complex ubiquitin ligase activity in vivo, as well as CTLH and CRA domains; plays role in anti-apoptosis; required for survival upon exposure to K1 killer toxin

Pathway information


  • location
    • cytoplasm
  • process
    • anti-apoptosis

References


  • Khoury, C.M., et al. (2008) A TSC22-like motif defines a novel antiapoptotic protein family, FEMS Yeast Res, 8, 540-563.
  • Madeo, F., et al. (2009) Caspase-dependent and caspase-independent cell death pathways in yeast, Biochem Biophys Res Commun, 382, 227-231.

Cross references


SGD:
UniProt:
InterPro:
CTLH, C-terminal LisH motif (IPR006595)
CTLH/CRA C-terminal to LisH motif domain (IPR024964)
RING-type zinc-finger, LisH dimerisation motif (IPR027370)
PSICQUIC View:
Gene Expression Atlas: