Result summary


Detailed summary for NUC1:

NUC1


Systematic name:
YJL208C
Description:
Major mitochondrial nuclease, has RNAse and DNA endo- and exonucleolytic activities; has roles in mitochondrial recombination, apoptosis and maintenance of polyploidy
Related info:
Kap123p, a protein involved in nuclear import, is required for Nuc1p-mediated death

References


  • Buttner, S., et al. (2007) Endonuclease G regulates budding yeast life and death, Mol Cell, 25, 233-246.
  • Rockenfeller, P. and Madeo, F. (2008) Apoptotic death of ageing yeast, Exp Gerontol, 43, 876-881.
  • Madeo, F., et al. (2009) Caspase-dependent and caspase-independent cell death pathways in yeast, Biochem Biophys Res Commun, 382, 227-231.
  • Carmona-Gutierrez, D., et al. (2010) Apoptosis in yeast: triggers, pathways, subroutines, Cell Death Differ, 17, 763-773.

Cross references


SGD:
UniProt:
InterPro:
DNA/RNA non-specific endonuclease (IPR001604)
DNA/RNA non-specific endonuclease, active site (IPR018524)
Extracellular Endonuclease, subunit A (IPR020821)
PSICQUIC View:
Gene Expression Atlas: